Description
Product Characteristics:
Acts as a transcriptional regulator. Together with NKX2-2, initiates transcriptional activation of NEUROD1. Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types (By similarity).
Subcellular location: Nucleus
Synonyms: ngn3, Atoh5, NGN-3, Math4B, bHLHa7, Neurogenin-3, Class A basic helix-loop-helix protein 7, Protein atonal homolog 5, NEUROG3
Target Information: The protein encoded by this gene is a basic helix-loop-helix (bHLH) transcription factor involved in neurogenesis. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of congenital malabsorptive diarrhea 4 (DIAR4).[provided by RefSeq, May 2010]