Description
Product Characteristics: Ppp2r2d is a B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment. Synonyms: Polyclonal Ppp2r2d antibody, Anti-Ppp2r2d antibody, protein phosphatase 2, regulatory subunit B, delta isoform antibody, 1300017E19Rik antibody, D7Ertd753e antibody, MDS026 antibody.
Target Information: cytosolic regulatory subunit that modifies protein phosphatase type 2A activity and subcellular localization