Description
Product Characteristics:
Human Rad1 is a component of a heterotrimeric PCNA like complex that also contains the Rad9 and Hus1 proteins. This complex is believed to be involved in cellular responses to DNA damage, possibly by associating with Rad17 and several components of the PCNA-loading heteropentamer, replication factor C. Human Rad1 exhibits significant homology to Rad1 from S. pombe, and its expression in yeast rad1 mutants has been shown to partially restore radiation resistance and G2 checkpoint activity. It has also been shown to possess exonuclease activity.
Subcellular location: Cell membrane
Synonyms: RAD, Ras-related associated with diabetes, RAD1, REM3, Cell cycle checkpoint protein Hrad1, Cell cycle checkpoint protein Rad 1 A / B, Cell cycle checkpoint protein RAD1, Checkpoint control protein HRAD1, Checkpoint control protein RAD1, DNA repair exonuclease, DNA repair exonuclease rad1, DNA repair exonuclease rad1 homolog, DNA repair exonuclease REC1, DNA repair protein RAD1, EC 3.1.11.2, Exonuclease homolog RAD1, GTP-binding protein RAD, hRAD 1, hRAD1, MGC77779, RAD 1, RAD, RAD1 homolog S. pombe, RAD1 homolog, Rad1 like DNA damage checkpoint, Rad1 like DNA damage checkpoint protein, RAD1, S. pombe, homolog of, Ras associated with diabetes, REC 1, REC1, RRAD, RAD_HUMAN.
Target Information: human homolog is a GTP-binding protein