Description
Product Characteristics:
Involved in regulating cell motility and cell-matrix interactions. May inhibit cell growth through suppression of cell proliferation.
Subcellular location: Cytoplasm, Cell membrane, Extracellular matrix
Synonyms: GlialCAM, HECAM_HUMAN, HEPACAM, Hepatocyte cell adhesion molecule, Protein hepaCAM.
Target Information: The protein encoded by this gene is a single-pass type I membrane protein that localizes to the cytoplasmic side of the cell membrane. The encoded protein acts as a homodimer and is involved in cell motility and cell-matrix interactions. The expression of this gene is downregulated or undetectable in many cancer cell lines, so this may be a tumor suppressor gene. [provided by RefSeq, Jul 2011]