Description
Product Characteristics:
The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy.
Synonyms: Actinin associated LIM protein, Actinin-associated LIM protein, Alpha actinin 2 associated LIM protein, Alpha-actinin-2-associated LIM protein, DKFZp686L0362, Enigma homolog, PDLI3_HUMAN, PDLIM 3, PDLIM-3, PDLIM3, ALP, PDZ and LIM domain 3, PDZ and LIM domain protein 3.
Target Information: The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. [provided by RefSeq, Apr 2012]