Description
Product Characteristics:
Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of GPR56 in the developing brain and binding to GPR56 inhibits neuronal migration and activates the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12.
Subcellular location: Secreted, Extracellular matrix
Synonyms: EDS4A, Collagen alpha-1(III) chain, COL3A1
Target Information: catalyzes the preferential cleavage of Arg-Gly\, activates fibrinogen to fibrin and releases fibrinopeptides A and B\, involved in blood coagulation and wound repair [RGD, Feb 2006]