Description
Product Characteristics:
Potential mitochondrial transporter. May play a role in apoptosis.Tissue specificity: Widely expressed with a predominant expression in brain.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: Cell proliferation inducing protein 60, CGI-64, CGI64, Mitochondrial carrier homolog 1, Mitocondrial Carrier Homolog 1, MTCH 1, Mtch1, MTCH1_HUMAN, Presenilin Associated Protein, Presenilin-associated protein, PSAP.
Target Information: This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Oct 2012]