Description
Product Characteristics:
KLF2 Activates transcription by binding to the CACCC box in the beta-globin gene promoter.
Subcellular location: Nucleus
Synonyms: LKLF, Krueppel-like factor 2, Lung krueppel-like factor, KLF2
Target Information: Kruppel-like factors (KLFs) are a family of broadly expressed zinc finger transcription factors. KLF2 regulates T-cell trafficking by promoting expression of the lipid-binding receptor S1P1 (S1PR1\, MIM 601974) and the selectin CD62L (SELL\, MIM 153240) (summary by Weinreich et al., 2009 [PubMed 19592277]).[supplied by OMIM, Feb 2011]