Description
Product Characteristics:
Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels, acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL.
Synonyms: Hematopoietically expressed homeobox, Hematopoietically-expressed homeobox protein HHEX, HEX, HHEX, HHEX_HUMAN, HMPH, Homeobox protein HEX, Homeobox protein PRH, HOX11L PEN, PRH, PRHX.
Target Information: This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation. [provided by RefSeq, Jul 2008]