Description
Product Characteristics:
Natriuretic peptide receptor C does not exhibit guanylate cyclase activity. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction.
Subcellular location: Cell membrane
Synonyms: ANP C, ANPC, ANPRC, Atrial natriuretic peptide C type receptor, Atrionatriuretic peptide receptor C, Natriuretic peptide receptor C/guanylate cyclase C, NPR 3, NPR C, NPR3, NPRC, ANPRC_HUMAN.
Target Information: This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]