Description
Product Characteristics:
Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Subcellular location: Cytoplasm
Synonyms: PI5, maspin, Serpin B5, Peptidase inhibitor 5, PI-5, SERPINB5
Target Information: may act as a tumor suppressor [RGD, Feb 2006]