Description
Product Characteristics:
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.Tissue specificity:Detected in spleen, thymus, testis, ovary, small intestine and colon, with highest levels of expression in testis and ovary.
Subcellular location: Cytoplasm
Synonyms: 26S proteasome-associated UCH interacting protein 1, 26S proteasome-associated UCH37-interacting protein 1, Expressed-Xq28STS protein, HAUS augmin-like complex subunit 7, Haus7, HAUS7_HUMAN, UCH37 interacting protein 1, UCHL5 interacting protein, UCHL5-interacting protein, UCHL5IP, UIP1, X-linked protein STS1769.
Target Information: This gene encodes a subunit of the augmin complex, which regulates centrosome and mitotic spindle integrity, and is necessary for the completion of cytokinesis. The encoded protein was identified by interaction with ubiquitin C-terminal hydrolase 37. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]