Description
Product Characteristics:
The product of the GAJ gene associates with HOP2 to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 and DMC1. Both the MND1 and HOP2 genes are indispensable for meiotic recombination.
Subcellular location: Nucleus
Synonyms: GAJ protein, Homolog of yeast MND1, Meiotic nuclear division 1, S. cerevisiae. homolog of antibody, Meiotic nuclear division protein 1 homolog, Meiotic nuclear divisions 1 homolog S. cerevisiae, Meiotic nuclear divisions 1 homolog, MGC134110, MND1, RGD1309007, 2610034E18Rik, AI591601.
Target Information: The product of the MND1 gene associates with HOP2 (MIM 608665) to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 (MIM 179617) and DMC1 (MIM 602721) (Chi et al., 2007 [PubMed 17639080]). Both the MND1 and HOP2 genes are indispensable for meiotic recombination.[supplied by OMIM, Mar 2008]