Description
Product Characteristics:
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008].
Subcellular location: Secreted
Synonyms: Kalikrein, Kallikrein 13, KLK 13, KLK-13, Kallikrein-13, Kallikrein L4, Kallikrein Like 4, Kallikrein like 4 variant included, Kallikrein like gene 4, Kallikrein like protein 4, Kallikrein related peptidase 13, Kallikrein-13, Kallikrein-like protein 4, KLK-L4, KLK13, KLK13_HUMAN, KLKL 4, KLKL4.
Target Information: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Expression of this gene is regulated by steroid hormones and may be useful as a marker for breast cancer. An additional transcript variant has been identified, but its full length sequence has not been determined. [provided by RefSeq, Jul 2008]