Description
Product Characteristics:
ANKRD28 selectively inhibits the phosphatase activity of PPP1C and targets PPP1C to modulate HNRPK phosphorylation. It contains twenty seven ANK repeats. There are two named isoforms.
Subcellular location: Nucleus
Synonyms: ANKRD 28, ANKRD-28, Ankyrin repeat domain 28, KIAA0379, Phosphatase interactor targeting K protein, Phosphatase interactor targeting protein hnRNP K, PITK, ANR28_HUMAN.
Target Information: Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. Selectively inhibits the phosphatase activity of PPP1C. Targets PPP1C to modulate HNRPK phosphorylation