Description
Product Characteristics:
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
Subcellular location: Nucleus
Synonyms: CAAT box transcription factor, CCAAT binding transcription factor, CCAAT box binding transcription factor, CCAAT-box-binding transcription factor, CNFI C, CTF, CTF5, NF I, NF I/C, NF-I/C, NF1 C, NF1-C, NF1C, NFI, NFI-C, NFI/C, NFIC, NFIC_HUMAN, Nuclear factor 1, Nuclear factor 1 C type, Nuclear factor 1 C-type, Nuclear factor 1/C, Nuclear factor I/C, TGGCA binding protein, TGGCA-binding protein, Transcription factor NFIC.
Target Information: The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]