Description
Product Characteristics:
This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
Subcellular location: Cytoplasm, Nucleus
Synonyms: Caspase like protein, DKFZp434L132, MALT 1, MALT associated translocation, MALT lymphoma associated translocation, MALT lymphoma-associated translocation, Malt1, MALT1_HUMAN, MLT 1, MLT, MLT1, Mucosa associated lymphoid tissue lymphoma translocation gene 1, Mucosa associated lymphoid tissue lymphoma translocation protein 1, Mucosa-associated lymphoid tissue lymphoma translocation protein 1, Paracaspase.
Target Information: This gene has been found to be recurrently rearranged in chromosomal translocation with two other genes - baculoviral IAP repeat-containing protein 3 (also known as apoptosis inhibitor 2) and immunoglobulin heavy chain locus - in mucosa-associated lymphoid tissue lymphomas. The protein encoded by this gene may play a role in NF-kappaB activation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]