Description
Product Characteristics:
Converts big endothelin-1 to endothelin-1. May also have methyltransferase activity (By similarity). May play a role in amyloid-beta processing (By similarity).
Subcellular location: Cytoplasm, Cell membrane
Synonyms: EEF1AKMT4-ECE2 readthrough transcript protein, Methyltransferase-like region, Endothelin-converting enzyme 2 region, EEF1AKMT4-ECE2, EFCE2_HUMAN
Target Information: Endothelin-converting enzymes, such as ECE2 (EC 3.4.24.71), are type II metalloproteases that generate functionally pleiotropic members of the endothelin vasoactive peptide family (Lorenzo et al., 2001 [PubMed 11718899]).[supplied by OMIM, Mar 2008]