Description
Product Characteristics:
XAB2 protein (XPA binding protein 2) was first identified through its interaction with XPA, a key factor in nucleotide excision repair pathways. XAB2 therefore appears to be involved in transcription coupled DNA repair and transcription. Immunoprecipitation experiments have also demonstrated that a fraction of XAB2 interacts with the transcription coupled repair specific proteins CSA and CSB as well as with RNA polymerase II. Microinjection experiments with XAB2 resulted in the inhibition of both transcription coupled repair and transcription.
Subcellular location: Nucleus
Synonyms: 0610041O14Rik, adapter protein ATH 55, Adapter protein ATH-55, Ath55, AV025587, Crn related protein kim1, crn-related protein kim1, DKFZp762C1015, HCNP, HCNP protein, HCRN, KIAA1177, NTC90, PP3898, Pre-mRNA-splicing factor SYF1, Protein HCNP, RNA splicing factor, SYF1, SYF1 homolog, SYF1 homolog, RNA splicing factor, SYF1_HUMAN, Xab2, XPA binding protein 2, XPA-binding protein 2.
Target Information: Involved in transcription-coupled repair (TCR), transcription and pre-mRNA splicing