Description
Product Characteristics:
Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008].
Subcellular location: Secreted
Synonyms: FGL 1, Fgl1, FGL1_HUMAN, Fibrinogen like 1, Fibrinogen like protein 1, Fibrinogen related protein 1, Fibrinogen-like protein 1, Hepassocin, Hepatocellular carcinoma related sequence, Hepatocyte derived fibrinogen related protein 1, Hepatocyte-derived fibrinogen-related protein 1, HFREP 1, HFREP-1, HFREP1, HP 041, HP-041, HP041, LFIRE 1, LFIRE-1, LFIRE1, Liver fibrinogen related protein 1, Liver fibrinogen-related protein 1, MFIRE 1.
Target Information: Fibrinogen-like 1 is a member of the fibrinogen family. This protein is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins. However, this protein lacks the platelet-binding site, cross-linking region and a thrombin-sensitive site which are necessary for fibrin clot formation. This protein may play a role in the development of hepatocellular carcinomas. Four alternatively spliced transcript variants encoding the same protein exist for this gene. [provided by RefSeq, Jul 2008]