Description
Product Characteristics:
Glycerol 3 Phosphate Dehydrogenase is a homodimer and belongs to the NAD dependent Glycerol 3 Phosphate Dehydrogenase family.
Subcellular location: Cytoplasm
Synonyms: AI747587, cytoplasmic, EC 1.1.1.8, FLJ26652, G3PD, Gdc-1, Gdc1, Gdp1, Glycerol 3 phosphate dehydrogenase 1, Glycerol 3 phosphate dehydrogenase cytosolic, Glycerol 3 phosphate dehydrogenase soluble, Glycerol-3-phosphate dehydrogenase [NAD+], Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic, Glycerol-3-phosphate dehydrogenase 1 soluble, Glycerol-3-phosphate dehydrogenase, Glycerol-3-phosphate dehydrogenase, soluble, Glycerphosphate dehydrogenase, GPD-C, gpd1, Gpd1 protein, GPD2, Gpd3, GPDA_HUMAN, Gpdc, GPDH, GPDH-C, Gpdhc, KIAA4010, MGC93453, MGPD, mKIAA4010.
Target Information: This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]