Description
Product Characteristics:
HCK is a tyrosine kinase that is predominantly expressed in hemopoietic cell types. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils.
Subcellular location: Cytoplasm, Nucleus, Cell membrane
Synonyms: Bmk, Hck 1, Hemopoietic cell kinase, Hemopoietic cell kinase isoform p59 Hck, JTK 9, JTK9, MGC 18625, MGC18625, p59 HCK/p60 HCK, p59HCK/p60HCK, Tyrosine protein kinase HCK.
Target Information: The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon. [provided by RefSeq, Feb 2010]