Description
Product Characteristics: Sec31a is a putative membrane-associated endosomal phosphoprotein. Synonyms: Polyclonal Sec31a antibody, Anti-Sec31a antibody, SEC31 homolog A, S. cerevisiae antibody, VAP1 antibody, Sec31l1 antibody, MGC93320 antibody, Sec31a antibody.
Target Information: The protein encoded by this gene is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER). This protein was found to colocalize with SEC13, one of the other components of COPII, in the subcellular structures corresponding to the vesicle transport function. An immunodepletion experiment confirmed that this protein is required for ER-Golgi transport. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]