Description
Product Characteristics:
Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin. [provided by RefSeq, Jul 2008]
Subcellular location: Cell membrane
Synonyms: F2RL3, F2R Like Thrombin/Trypsin Receptor 3, Coagulation Factor II (Thrombin) Receptor-Like 3, Thrombin Receptor-Like 3, PAR-4, PAR4, Coagulation Factor II Receptor-Like 3, Proteinase-Activated Receptor-4, Proteinase-Activated Receptor 4, Protease-Activated Receptor-4, PAR4_HUMAN,
Target Information: Coagulation factor II (thrombin) receptor-like 3 (F2RL3) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL3 is also a member of the protease-activated receptor family. F2RL3 is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. F2RL3 is activated by thrombin and trypsin. [provided by RefSeq, Jul 2008]