Description
Product Characteristics:
Component of cohesin complex, a complex required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis.
Subcellular location: Nucleus
Synonyms: Cohesin Subunit SA 2, Cohesin subunit SA-2, DKFZp686P168, DKFZp781H1753, SA 2, SA2, SCC3 homolog 2, STAG 2, STAG 2, stag2, STAG2_HUMAN, Stromal antigen 2, FLJ25871, bA517O1.1.
Target Information: Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis- specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I (By similarity)