Description
Product Characteristics: The 34-2-12 antibody (also known as 34-2-12S) recognizes the alpha3 domain of the H-2D^[d]. The binding of the antibody to its epitope is independent of the alpha1 and alpha2 domains and beta2 microglobulin. It cross-reacts with cells of the C3H.LG/Ckc strain. Reactivity with other haplotypes (eg, b, f, k, p, q, r, s) has not been observed. Soluble mAb 34-2-12 blocks binding of the Ly-49A-expressing T lymphoma EL4 to immobilized H-2D[d]. However, further studies utilizing this mAb indicate that the alpha3 domain is not involved in the interaction between Ly-49A, or Ly-49G2, and H-2D[d].
Target Information: Please see product details or send an inquiry to antibodies-online for additional target information