Description
Product Characteristics:
Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1. Promotes neuronal cell death.
Subcellular location: Cytoplasm
Synonyms: DDIT4, DDIT4_HUMAN, Dig2, DKFZp564O2071, DNA damage inducible transcript 4, DNA damage inducible transcript 4 protein, DNA damage-inducible transcript 4 protein, FLJ20500, H 1 responsive protein RTP801, H 1 responsive RTP801, H-1 responsive protein RTP801, Protein regulated in development and DNA damage response 1, REDD 1, REDD-1, REDD1, RP11 442H21.1, RTP801.
Target Information: HIF-1-responsive gene that may protect some types of cells from hypoxia and H(2)O(2)-triggered apoptosis [RGD, Feb 2006]