Description
Product Characteristics:
This protein belongs to a G protein coupled heptahelical receptor subfamily named Endothelial Cell Differentiation Genes (EDG)that act as receptors for biologically active lysophospholipids. This group consists of two receptor subgroups specific for S1P and LPA respectively. EDG6 is the receptor for lysophospholipid sphingosine 1 phosphate (S1P). S1P elicits diverse physiological effect on most types of cells and tissues. EDG6 may be involved in cell migration processes that are specific for lymphocytes.
Subcellular location: Cell membrane
Synonyms: Endothelial dferentiation lysophosphatidic acid G protein coupled receptor 6, Endothelial dferentiation G protein coupled receptor 6, Endothelial dferentiation gene 6, LPC1, Lysophospholipid receptor C1, MGC129298, Putative G protein coupled receptor, S1P receptor 4, S1P receptor Edg6, S1P4, S1PR4, SLP4, Sphingosine 1 phosphate receptor 4, Sphingosine 1 phosphate receptor Edg6, S1PR4_HUMAN.
Target Information: This gene is a member of the endothelial differentiation, G-protein-coupled EDG receptor gene family. EDG receptors bind lysophospholipids or lysosphingolipids as ligands, and are involved in cell signalling in many different cell types. This EDG receptor gene is intronless and is specifically expressed in the lymphoid tissue. [provided by RefSeq, Jul 2008]