Description
Product Characteristics:
May play a role in mediating neutrophil activation and chemotaxis.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: 47 kDa actin binding protein, 47 kDa actin-binding protein, 52 kDa phosphoprotein, F actin binding and cytoskeleton associated protein, Leufactin leukocyte F-actin binding protein, Leufactin, Leukocyte F actin binding protein, Leukocyte specic protein 1, LSP 1, Lsp1, LSP1_HUMAN, Lymphocyte specic antigen WP34, Lymphocyte specic protein 1, Lymphocyte specic protein pp52, Lymphocyte-specic antigen WP34, Lymphocyte-specic protein 1, OTTHUMP00000014138, OTTHUMP00000014139, OTTHUMP00000014140, OTTHUMP00000069612, OTTHUMP00000069614, OTTHUMP00000069615, OTTHUMP00000069616, pp52, Protein pp52, S37 protein, WP 34, WP34.
Target Information: This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]