Description
Product Characteristics:
KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].
Subcellular location: Cytoplasm, Nucleus
Synonyms: Cytokeratin 18 phospho S60, p-Cytokeratin 18 phospho S60, Cell proliferation inducing gene 46 protein, Cell proliferation inducing protein 46, Cell proliferation-inducing gene 46 protein, CK 18, CK-18, CK18, CYK 18, CYK18, Cytokeratin 18, Cytokeratin endo B, Cytokeratin-18, Cytokeratin18, K 18, K18, K1C18_HUMAN, Keratin 18, Keratin D, Keratin type I cytoskeletal 18, keratin, type I cytoskeletal 18, Keratin-18, Keratin18, Kerd, KRT18.
Target Information: KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]