Description
Product Characteristics:
MAD2L2 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L2 is a homolog of MAD2L1.
Subcellular location: Cytoplasm, Nucleus
Synonyms: Homolog of REV7 S cerevisiae, HREV7, MAD2 homolog, MAD2 like 2, MAD2 mitotic arrest deficient like 2, MAD2B, Mitotic Arrest Deficient 2 L2, Mitotic arrest deficient homolog like 2, Mitotic arrest deficient like 2 yeast, Mitotic arrest deficient yeast homolog, Mitotic spindle assembly checkpoint protein MAD2B, REV 7, REV7, Weakly similar to Mitotic MAD2 protein S cerevisiae.
Target Information: The protein encoded by this gene is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. The encoded protein, which is similar to MAD2L1, is capable of interacting with ADAM9, ADAM15, REV1, and REV3 proteins. [provided by RefSeq, Jul 2008]