Description
Product Characteristics:
This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012].
Subcellular location: Cytoplasm, Cell membrane
Synonyms: Cyclooxygenase-1, Cyclooxygenase 1, COX-1, COX 1, COX1, Cyclooxygenase1, Prostaglandin-endoperoxide synthase-1, prostaglandin-endoperoxide synthase 1, PTGS-1, Prostaglandin G/H synthase 1 precursor, prostaglandin G/H synthase 1 isoform 1 precursor, Prostaglandin H2 synthase 1, PGH synthase 1, PGHS-1, PHS 1, PGH1_HUMAN, PTGS1, Prostaglandin G/H synthase 1 precursor.
Target Information: This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]