Description
Product Characteristics:
DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).
Subcellular location: Nucleus
Synonyms: HMG1, HMG3, SBP-1, High mobility group protein B1, High mobility group protein 1, HMG-1, HMGB1
Target Information: a transcriptional regulator that may play a central role in the stabilization and/or assembly of several multifunctional complexes through protein-protein interactions [RGD, Feb 2006]