Description
Product Characteristics:
Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis.
Subcellular location: Nucleus
Synonyms: CAPD3, hcp-6, CAP-D3, hHCP-6, hCAP-D3, Condensin-2 complex subunit D3, Non-SMC condensin II complex subunit D3, NCAPD3, KIAA0056
Target Information: Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPD3 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003 [PubMed 14532007]).[supplied by OMIM, Mar 2008]