Description
Product Characteristics:
Tissue specificity:Widely expressed. Most abundant in testis, skeletal muscle, and heart.
Subcellular location: Cytoplasm
Synonyms: PP2C, MGC1675, MGC2870, PP2C gamma, PP2C-gamma, PP2CG, PPM1G, PPM1G_HUMAN, PPP2CG, Protein phosphatase 1C, Protein phosphatase 1G, Protein phosphatase 2 catalytic subunit gamma isoform, Protein phosphatase 2C gamma isoform, Protein phosphatase 2C isoform gamma, Protein phosphatase magnesium dependent 1 gamma, Protein phosphatase magnesium-dependent 1 gamma.
Target Information: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors, which is important for the formation of functional spliceosome. Studies of a similar gene in mice suggested a role of this phosphatase in regulating cell cycle progression. [provided by RefSeq, Apr 2010]