Description
Product Characteristics:
Cell surface receptor that may play a role in the innate and adaptive immune response.
Subcellular location: Cytoplasm, Cell membrane, Extracellular matrix
Synonyms: TLT1, TLT-1, PRO3438, GLTL1825, dJ238O23.3, Trem-like transcript 1 protein, Triggering receptor expressed on myeloid cells-like protein 1, TREML1, UNQ1825/PRO3438
Target Information: This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants [provided by RefSeq, Nov 2012]