Description
Product Characteristics:
The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Sep 2011]
Subcellular location: Cytoplasm
Synonyms: 17 kDa PKC potentiated inhibitory protein of PP1, CPI 17 alpha, CPI 17, CPI 17alpha, CPI17, CPI-17, PKC potentiated inhibitory protein of PP1, PPP1INL, PPP1R14A, Protein phosphatase 1, Protein phosphatase 1 regulatory inhibitor subunit 14A, Protein phosphatase 1 regulatory subunit 14A, Regulatory subunit 14A, 17 kDa PKC-potentiated inhibitory protein of PP1, 17-KDa protein, 17 kDa PKC potentiated inhibitory protein of PP1, PKC potentiated inhibitory protein of PP1, PKC potentiated inhibitory protein of PP1, 17-KD, PP14A_HUMAN, Protein kinase C-potentiated inhibitor of protein phosphatase 1, 17-KD, Protein kinase C-potentiated inhibitor protein of 17 kDa, Protein phosphatase 1, Protein phosphatase 1 regulatory inhibitor subunit 14A, Regulatory subunit 14A.
Target Information: The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Sep 2011]