Description
Product Characteristics:
Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway.
Subcellular location: Cytoplasm, Nucleus
Synonyms: ICAT, Beta-catenin-interacting protein 1, Inhibitor of beta-catenin and Tcf-4, CTNNBIP1
Target Information: The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]