Description
Product Characteristics:
BTG2 is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. BTG2 is involved in the regulation of the G1/S transition of the cell cycle. It modulates transcription regulation mediated by ESR1(referenced from Entrez Gene). BTG2 expression is induced in vivo during neurogenesis, and the gene is transiently expressed in vitro in rat pheochromocytoma PC12 cells after induction of neuronal differentiation by addition of nerve growth factor (NGF), suggesting that BTG2 is functionally significant during the neuronal differentiation process (PMID: 12360398).
Subcellular location: Secreted
Synonyms: BTG2_HUMAN, Protein BTG2, BTG family member 2, NGF-inducible anti-prolerative protein PC3, pheochromacytoma cell-3, nerve growth factor-inducible anti-prolerative, B-cell translocation gene 2, BTG2, TIS21, PC3, TIS21.
Target Information: The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein is involved in the regulation of the G1/S transition of the cell cycle. [provided by RefSeq, Jul 2008]