Description
Product Characteristics:
RIP2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. It contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli.
Synonyms: Receptor interacting protein 2, Receptor interacting serine threonine kinase 2, Receptor interacting serine/threonine protein kinase 2, RICK, RIP 2, RIP LIKE INTERACTING CLARP KINASE, RIPK 2, RIPK2, TNFRSF, CARD 3, CARD carrying kinase, CARD CONTAINING ICE ASSOCIATED KINASE, CARD containing IL 1 beta ICE kinase, CARD containing IL1 beta ICE kinase, CARD containing interleukin 1 beta converting enzyme ICE associated kinase, CARD containing interleukin 1 beta converting enzyme associated kinase, CARD3, CARDIAK, CCK, CLARP kinase, GIG 30, GIG30, Growth inhibiting gene 30, Receptor interacting protein RIP like interacting caspase like apoptosis regulatory protein CLARP kinase.
Target Information: This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappaB and inducer of apoptosis in response to various stimuli. [provided by RefSeq, Jul 2008]