Description
Product Characteristics:
Glycerol kinase catalyzes the formation of glycerol 3 phosphate from ATP and glycerol. Dihydroxyacetone and L glyceraldehyde can also act as acceptors, UTP and, in the case of the yeast enzyme, ITP and GTP can act as donors. It provides a way for glycerol derived from fats or glycerides to enter the glycolytic pathway.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: ATP glycerol 3 phosphotransferase, GK, GK1, GK2, GKD, Glycerokinase, Glycerol kinase, Glycerol kinase deficiency, ATP:glycerol 3-phosphotransferase, GLPK_HUMAN.
Target Information: The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]