Description
Product Characteristics:
This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants.
Subcellular location: Nucleus
Synonyms: 75 kDa bromodomain protein, BP75, BRD 7, BRD7, BRD7_HUMAN, Bromodomain containing 7, bromodomain containing protein 7, Bromodomain-containing protein 7, CELTIX 1, CELTIX1, NAG4, Protein CELTIX-1.
Target Information: This gene encodes a protein which is a member of the bromodomain-containing protein family. The product of this gene has been identified as a component of one form of the SWI/SNF chromatin remodeling complex, and as a protein which interacts with p53 and is required for p53-dependent oncogene-induced senescence which prevents tumor growth. Pseudogenes have been described on chromosomes 2, 3, 6, 13 and 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010]