Description
Product Characteristics:
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
Subcellular location: Cytoplasm, Cell membrane
Synonyms: Alpha PAK, Alpha-PAK, MGC130000, MGC130001, p21 activated kinase 1, p21 protein Cdc42/Rac activated kinase 1, p21-activated kinase 1, p21/Cdc42/Rac1 activated kinase 1 yeast Ste20 related, p21/Cdc42/Rac1 activated kinase 1, p21/Cdc42/Rac1-activated kinase 1 STE20 homolog, yeast, p65 PAK, p65-PAK, PAK alpha, PAK-1, Pak1, PAK1_HUMAN, Paka, PAKalpha, Protein kinase MUK2, Rac/p21-activated kinase, Serine/threonine-protein kinase PAK 1, STE20 homolog yeast, STE20 homolog yeast.
Target Information: This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]