Description
Product Characteristics:
The transmembrane glycoprotein Tumor endothelial marker 1 (TEM1) is highly expressed in tumor endothelial cells however it is barely detectable on normal endothelial cells. It is believed to play a role in tumor angiogenesis. It is expressed in stromal fibroblasts, metastatic hepatic lesions and during angiogenesis of corpus luteum formation and wound healing. TEM1 is being investigated as a potential target for cancer treatment.
Subcellular location: Cell membrane
Synonyms: TEM1, CD164L1, Endosialin, Tumor endothelial marker 1, CD248
Target Information: May play a role in angiogenesis or vascular function