Anti-COX2 / Cyclooxygenase 2 antibody [EP1978Y] ab62331 from Abcam

Product Specs
ItemAnti-COX2 / Cyclooxygenase 2 antibody [EP1978Y]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab62331
Antibody TypePrimary
Quantity10 UL, 40 UL, 100 UL
CloneEP1978Y
ClonalityMonoclonal
ApplicationsWestern blot
HostRabbit
IsotypeIgG
Conjugate/TagUnconjugated
Gene NamePTGS2
ReactivityHuman, Mouse
TargetCOX2 / Cyclooxygenase 2

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Exosomal miR-663b from “M1” macrophages promotes pulmonary artery vascular smooth muscle cell dysfunction through inhibiting the AMPK/Sirt1 axisAging (Albany NY)May 15, 2023Honghong Ma, Yang Yu, Lirong Mo, Qian Chen, Hui Dong, Yan Xu, Bing Zhuanmembranes encompassed Anti-iNOS (Abcam, 1:1000, ab178945, Shanghai, China), Anti-COX2 (Abcam, 1:1000, ab62331), Anti-Nrf2 (Abcam, ab62352, 1:1000), Anti-Trx-1 (Abcam, ab26320, 1:1000), Anti-HO-1 (Abcam, ab68477,

(2) Î±-Cyperone Protects Cardiomyocytes against Oxygen-Glucose Deprivation-Induced Inflammation and Oxidative Stress by Akt/FOXO3a/NF-ÎºB PathwayDisease MarkersAugust 29, 2022Feiqun Yao, Qian Zhuanti-C-Caspase3 (Abcam, 1 : 1000, ab32042), anti-iNOS (Abcam, 1 : 1000, ab178945), anti-COX2 (Abcam, 1 : 1000, ab62331), and anti-GAPDH (Abcam, 1 : 1000, ab ab9485) antibodies overnight at 4°C. Subsequently, the membranes

(3) Reversing PD-1 Resistance in B16F10 Cells and Recovering Tumour Immunity Using a COX2 InhibitorCancers (Basel)August 26, 2022Chenyu Pi, Ping Jing, Bingyu Li, Yan Feng, Lijun Xu, Kun Xie, Tao Huang, Xiaoqing Xu, Hua Gu, Jianmin Fanganti-GAPDH (AF1186; Beyotime), anti-rabbit-IgG-HRP (A120-111P; Bethyl, Montgomery, TX, USA), and anti-COX2 (ab62331; Abcam, Cambridge, UK). 2.7. Statistical Analysis Statistical analyses were performed using GraphPad

(4) MicroRNA-155 acts as an anti-inflammatory factor in orbital fibroblasts from Graves’ orbitopathy by repressing interleukin-2-inducible T-cell kinasePLOS ONEAugust 18, 2022Yeon Jeong Choi, Charm Kim, Eun Woo Choi, Seung Hun Lee, Min Kyung Chae, Hyung Oh Jun, Bo-Yeon Kim, Jin Sook Yoon, Sun Young JangUSA). The samples were probed overnight with primary antibodies (IL-6, #12153; Cell Signaling; COX-2, #ab62331; ICAM-1, #ab53013; IL-1β, #ab9722; TNF-α, #ab6671, Abcam; IL-17, #sc-374218; Santa Cruz Biotechnology,

(5) Selenium Yeast and Fish Oil Combination Diminishes Cancer Stem Cell Traits and Reverses Cisplatin Resistance in A549 Sphere CellsNutrientsAugust 7, 2022I-Chun Lai et al.Cell Signaling Technology, Inc. (Danvers, MA, USA). Primary antibodies for CHOP (ab11419), GRP78 (ab108613), COX-2 (Ab62331), CD133 (ab19898), vimentin (ab16700), N-cadherin (ab76011), YAP (ab52771), Active YAP (ab205270), Bcl-2

(6) Dim Blue Light at Night Induces Spatial Memory Impairment in Mice by Hippocampal Neuroinflammation and Oxidative StressAntioxidants (Basel, Switzerland)June 22, 2022Liu Q, Wang Z, Cao J, Dong Y, Chen Y.then incubated in rabbit or mouse primary antibodies (iNOS, 1:1000, ab283655, Abcam; COX2, 1:1000, ab62331, Abcam; TLR4, 1:1000, sc-293072, Santa Cruz Biotechnology; p65, 1:1000, ab16502, Abcam; pp65, 1:1000,

(7) Dexmedetomidine Attenuates Ferroptosis-Mediated Renal Ischemia/Reperfusion Injury and Inflammation by Inhibiting ACSL4 via α2-ARFrontiers in PharmacologyJune 14, 2022Wen-hui Tao et al.corresponding primary antibodies: GPx4 antibody (P02794, Abways), ACSL4 antibody (O60488, Abways); COX2 (ab62331, Abcam); β-tubulin antibody (86,298, Cell Signalling Technology). Next, the membranes were washed and

(8) Protective Effect of Prim-O-Glucosylcimifugin on Ulcerative Colitis and Its MechanismFrontiers in PharmacologyMay 18, 2022Yu Yin, Kunjian Liu, Guofeng Li(3033), NF-κB IκB-α (L35A5), NF-κB p-IκB-α (ser32) JNK (9252), p-JNK (4668), β-actin (3700), COX-2 (ab62331), iNOS (ab178945), ZO-1 (D6L1E), Occludin (ab216327), and Claudin-3 (ab15102) were provided by Abcam

(9) Inhibitory effect of lovastatin on human lung cancer cell proliferation by regulating the ERK1/2 and COX-2 pathwaysTranslational Cancer ResearchApril 1, 2022Sha Liu, Ping Yang, Mingkung Wang, Shuang Zhang, Jie Wang, Tao Pan, Ping ZhouMassachusetts, USA), pERK1/2 (ab223500, Abcam), c-JUN (ab31419, Abcam), p-c-JUN (ab32385, Abcam), Cox-2 (ab62331, Abcam), BCL-2(ab196495, Abcam), Bax (ab53154, Abcam) and β-Catenin (ab32575, Abcam). Immunofluorescence

(10) Silencing lncRNA SLC16A1-AS1 Induced Ferroptosis in Renal Cell Carcinoma Through miR-143-3p/SLC7A11 SignalingTechnology in Cancer Research & TreatmentFebruary 15, 2022Yan ze Li, Heng Cheng Zhu, Yang Du, Hong chao Zhao, Lei WangThe membranes were incubated with antibodies against GPX4 (ab125066, Abcam), cyclooxygenase 2 (COX2; ab62331, Abcam), ACSL4 (ab155282, Abcam), and glyceraldehyde 3-phosphate dehydrogenase (ab8245, Abcam), and

(11) MITD1 Deficiency Suppresses Clear Cell Renal Cell Carcinoma Growth and Migration by Inducing Ferroptosis through the TAZ/SLC7A11 PathwayOxidative medicine and cellular longevityJanuary 1, 2022Zhang Y, Li Y, Qiu Q, Chen Z, Du Y, Liu X.SLC7A11 (ab37185, Abcam), glutathione peroxidase 4 (GPX4; ab125066, Abcam), cyclooxygenase 2 (COX2; ab62331, Abcam), acyl-CoA synthetase long-chain family member 4 (ACSL4; ab155282, Abcam), and glyceraldehyde

(12) Curcumin Improves Keratinocyte Proliferation, Inflammation, and Oxidative Stress through Mediating the SPAG5/FOXM1 Axis in an In Vitro Model of Actinic Dermatitis by UltravioletDisease markersJanuary 1, 2022Chen Q, Tang Y, Deng H, Liang B, Li H, Li Z, Zhu H, Chen L.anti-Nrf2 (Abcam, 1 : 1000, ab62352), anti-HO-1 (Abcam, 1 : 1000, ab52947), anti-COX2 (Abcam, 1 : 1000, ab62331), anti-iNOS (Abcam, 1 : 1000, ab178945), anti-p-NF-κB (Abcam, 1: 1000, ab76302), anti-NF-κB (Abcam,

(13) Peroxisome Proliferator-Activated Receptor α Activation Protects Retinal Ganglion Cells in Ischemia-Reperfusion RetinasFrontiers in MedicineDecember 23, 2021Fei Yao, Xuan Zhang, Xueyan Yao, Xiaohua Ren, Xiaobo Xia, Jian Jiang, Lexi Dingantibodies: anti-PPARα (ab215270; Abcam; 1:1,000), anti-GFAP (ab33922; Abcam; 1:1,000), anti-COX2 (ab62331; Abcam; 1:1,000), and anti-β-actin (GB12001; Servicebio; 1:3,000). The expression levels of PPARα, GFAP

(14) CoCrMo-Nanoparticles induced peri-implant osteolysis by promoting osteoblast ferroptosis via regulating Nrf2-ARE signalling pathwayCell proliferationDecember 1, 2021Xu Y, Sang W, Zhong Y, Xue S, Yang M, Wang C, Lu H, Huan R, Mao X, Zhu L, et al.Proteintech), HO‐1 (10701–1‐AP, Proteintech), NQO‐1 (11451–1‐AP, Proteintech), GPX4 (ab125066, Abcam), COX2 (ab62331, Abcam), ACSL4 (ab155282, Abcam), Keap1 (ab227828, Abcam), α‐tubulin (3873, Cell Signalling Technology),

(15) Gold nanoparticles alleviates the lipopolysaccharide-induced intestinal epithelial barrier dysfunctionBioengineeredSeptember 15, 2021Zhen Wang, Yinya Cao, Kangzhen Zhang, Zhirui Guo, Ying Liu, Ping Zhou, Zhengxia Liu, Xiang Luanti-occludin (#ab216327, 1/1000; Abcam), anti-iNOS (#ab178945, 1/1000; Abcam), anti-cyclooxygenase-2 (COX2; #ab62331, 1/1000; Abcam), anti-phosphorated IκB kinase alpha/beta (p-IKKα/β; #2697, 1/1000; Cell signaling),

(16) Inhibition of Acyl-CoA Synthetase Long-Chain Family Member 4 Facilitates Neurological Recovery After Stroke by Regulation FerroptosisFrontiers in Cellular NeuroscienceApril 6, 2021Junmin Chen, Lan Yang, Lianxia Geng, Junna He, Lei Chen, Qian Sun, Jing Zhao, Xiaopeng WangCat#ab125066, RRID: AB_10973901), ACSL4 (1:1000, Abcam Cat# ab155282, RRID: AB_2714020), COX2 (1:800, Abcam Cat#ab62331, RRID: AB_942121) and GAPDH (1:10000, Bioworld Technology Cat#AP0063, RRID: AB_2651132). On the second

(17) LncRNA PROX1-AS1 Facilitates Gastric Cancer Progression via miR-877-5p/PD-L1 AxisCancer Management and ResearchMarch 19, 2021TianWei Guo, Wei Wang, YueXia Ji, Min Zhang, GuoYing Xu, Sen Lin(ab196495, 1:1000), cleaved caspase-3 (ab49822, 1:1000), cleaved caspase-9 (ab2324, 1:1000), Cox-2 (ab62331, 1:1000), MMP-2 (ab86607, 1:1000), MMP-9 (ab38898, 1:1000), PD-L1 (AB213524, 1:1000) and GAPDH (ab9435, 1:1000).

(18) Menthol Targeting AMPK Alleviates the Inflammatory Response of Bovine Mammary Epithelial Cells and Restores the Synthesis of Milk Fat and Milk ProteinFrontiers in immunologyJanuary 1, 2021Liu S, Guo W, Jia Y, Ye B, Liu S, Fu S, Liu J, Hu G.CAT:20536-1-AP) purchased from Proteintech. Heme Oxygenase-1(HO-1) (1:1000, CAT : GK284419-11), COX-2(1:1000, CAT:ab62331) and INOS (1:1000, CAT:ab1532) purchased from Abcam. The secondary antibodies used in this study, including

(19) Sirt3 Maintains Microvascular Endothelial Adherens Junction Integrity to Alleviate Sepsis-Induced Lung Inflammation by Modulating the Interaction of VE-Cadherin and β-CateninOxidative medicine and cellular longevityJanuary 1, 2021Chen DQ, Shen MJ, Wang H, Li Y, Tang AL, Li S, Xiong MC, Guo Y, Zhang GQ.matrix metallopeptidase-7 (MMP-7, 1 : 400, ab5706; Abcam, USA), and cyclooxygenase-2 (COX-2, 1 : 1000, ab62331, Abcam, USA). α-Tubulin was purchased from the Proteintech Company (Hubei, China). The secondary antibodies

(20) Shenkang Injection and Its Three Anthraquinones Ameliorates Renal Fibrosis by Simultaneous Targeting IƙB/NF-ƙB and Keap1/Nrf2 Signaling PathwaysFrontiers in pharmacologyJanuary 1, 2021Luo LP, Suo P, Ren LL, Liu HJ, Zhang Y, Zhao YY.phosphorylated IƙBα (p-IκBα, 2859, Cell Signaling Technology, United States), gene cyclooxygenase 2 (COX-2, ab62331, Abcam, United States), monocyte chemotactic protein-1 (MCP-1, ab7202, Abcam, United States), inducible

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11/8/2021Easy to Optimize COX2 Antibody Wei Yang SitThis antibody is used to detect for the changes in the protein expression level of COX 2 protein through western blot.

Anti-COX2 / Cyclooxygenase 2 antibody [EP1978Y] from Abcam

Abcam

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Anti-COX2 / Cyclooxygenase 2 antibody [EP1978Y] from Abcam

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