Anti-p16 ARC antibody [EP1551Y] ab51243 from Abcam

Product Specs
ItemAnti-p16 ARC antibody [EP1551Y]
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab51243
Antibody TypePrimary
IsotypeIgG
ApplicationsImmunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot
Quantity10 UL, 40 UL, 100 UL
ClonalityMonoclonal
CloneEP1551Y
HostRabbit
Conjugate/TagUnconjugated
Gene NameARPC5
ValidationKnockOut Validated
ReactivityHuman, Mouse, Rat
Targetp16 ARC

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Dietary neoagarotetraose extends lifespan and impedes brain aging in mice via regulation of microbiota-gut-brain axisJournal of advanced researchOctober 1, 2023Li T, Yang S, Liu X, Li Y, Gu Z, Jiang Z.(Ser2448, p-mTOR; CST, cat. number 5536T), p21 (Abcam, cat. number ab188224), p16 (Abcam, cat. number ab51243), ZO-1 (Abcam, cat. number ab216880), Occludin (Abcam, cat. number ab216327), p38 MAPK (CST, cat. number

(2) Radiation Induces Bone Microenvironment Disruption by Activating the STING-TBK1 PathwayMedicina (Kaunas, Lithuania)July 16, 2023Wang Y, Ren L, Xu L, Wang J, Zhai J, Zhu G.with 5% BSA (cat.no. V900933; Sigma-Aldrich; Merck KGaA) for 30 min. Primary p16 antibody (cat. no. ab51243; Abcam, Cambridge, UK; 1:1000) and p21 antibody (cat. no. ab109199; Abcam; 1:1000) were then incubated

(3) CPEB2 enhances cell growth and angiogenesis by upregulating ARPC5 mRNA stability in multiple myelomaJournal of Orthopaedic Surgery and ResearchMay 26, 2023Piaorong Zeng, Fujue Wang, Xingxing Long, Yixiong Cao, Feng Wen, Junjun Li, Zeyu Luononfat milk, and incubated with anti-CPEB2 (ab222070, 1:100, Abcam, Cambridge, MA, USA), anti-ARPC5 (ab51243, 1:5000, Abcam) or anti-GAPDH (ab9485, 1:2500, Abcam). After hatched with secondary antibody (ab205718,

(4) Clinical-grade human umbilical cord-derived mesenchymal stem cells improved skeletal muscle dysfunction in age-associated sarcopenia miceCell Death & DiseaseMay 12, 2023Chao Wang, Bichun Zhao, Jinglei Zhai, Ailin Wang, Ning Cao, Tuling Liao, Ruyu Su, Lijuan He, Yanhua Li, Xuetao Pei, et al.actin (Abcam, USA, ab8226), Anti-Cleaved LC3B (Sigma, Germany, L7S43), Anti-ARPC5/p16 ARC (Abcam, USA, ab51243), p53 (1C12) Mouse mAb (Cell Signaling Technology, USA, 1C12). Origin images of all western blot have

(5) Comparison of therapeutic effects of mesenchymal stem cells derived from superficial and deep subcutaneous adipose tissuesStem Cell Research & TherapyMay 4, 2023Naoki Ishiuchi, Ayumu Nakashima, Satoshi Maeda, Yoshie Miura, Kisho Miyasako, Kensuke Sasaki, Toshio Uchiki, Ayano Sasaki, Shogo Nagamatsu, Naoki Nakao, et al.previously described methods [15]. A rabbit monoclonal anti-p16INK4a antibody (Abcam, Cambridge, UK, ab51243, 1:2500), rabbit monoclonal anti-p21WAF1/CIP1 antibody (Abcam, ab109199, 1:1000), rabbit monoclonal

(6) MicroRNA-19b-3p dysfunction of mesenchymal stem cell-derived exosomes from patients with abdominal aortic aneurysm impairs therapeutic efficacyJournal of nanobiotechnologyApril 26, 2023Zhang Y, Huang X, Sun T, Shi L, Liu B, Hong Y, Fu QL, Zhang Y, Li X.anti-CD81 (ab109201, Abcam), anti-TSG101 (ab125011, Abcam), Calnexin (10427-2-AP, Proteintech), anti-p16 (ab51243, Abcam), anti-p21 (ab109199, Abcam), anti-p-Drp1 (ser616) (3455, CST), anti-Drp1 (14,647, CST), anti-p-ERK1/2

(7) Effect of Lacking ZKSCAN3 on Autophagy, Lysosomal Biogenesis and SenescenceInternational Journal of Molecular SciencesApril 24, 2023Xiao-Min Li, Jun-Hao Wen, Ze-Sen Feng, Yun-Shan Wu, Dong-Yi Li, Shan Liang, Dan Wu, Hong-Luan Wu, Shang-Mei Li, Zhen-Nan Ye, et al.purchased from Abcam (Ab56416, Cambridge, UK). The primary antibody against p16 was obtained from Abcam (Ab51243, Cambridge, UK). The primary antibody against lamin B1 was purchased from Abcam (Ab16048, Cambridge,

(8) Sesamin Metabolites Suppress the Induction of Cellular SenescenceNutrientsMarch 27, 2023Chie Araki, Daisuke Takemoto, Yoshinori Kitagawa, Norifumi Tateishi, Tomohiro Rogi, Takayuki Izumo, Shimpei Kawamoto, Hiroshi Shibata, Eiji Hara, Masaaki Nakaimanufacturer’s instructions, the membrane was incubated together with primary antibody ARPC5/p16 ARC (ab51243, Abcam, Cambridge, UK) overnight at 4 °C. After washing several times in TBS containing 0.05% Tween-20,

(9) Attenuation of Alzheimer’s brain pathology in 5XFAD mice by PTH1-34, a peptide of parathyroid hormoneAlzheimer's Research & TherapyMarch 14, 2023Li Chen, Lei Xiong, Lingling Yao, Jinxiu Pan, Emily Arzola, Xiaojuan Zhu, Lin Mei, Wen-Cheng Xionganalyzed using NIH ImageJ software. Primary antibodies used were as follows: IBA1 (ab178846, rabbit), p16 (ab51243, rabbit), p53 (ab131442, rabbit), and anti-beta Actin (ab8226, mouse) from Abcam (Cambridge, MA, USA);

(10) Metformin regulates chondrocyte senescence and proliferation through microRNA-34a/SIRT1 pathway in osteoarthritisJournal of orthopaedic surgery and researchMarch 13, 2023Yan S, Dong W, Li Z, Wei J, Han T, Wang J, Lin F.Membranes were blocked with 5% skim milk and then incubated with primary antibodies against P16 (1:1000, ab51243, Abcam), ACAN (1:500, ab3778, Abcam), MMP13 (1:1000, #69,926, CST), IL-6 (1:1000, 66,146-1-Ig, Proteintech),

(11) A NOTCH1 Mutation Found in a Newly Established Ovarian Cancer Cell Line (FDOVL) Promotes Lymph Node Metastasis in Ovarian CancerInternational journal of molecular sciencesMarch 7, 2023Jiang W, Ouyang X, Jiang C, Yin L, Yao Q, Pei X, Ji Z, Li M, Song S, Yang W, et al.to routine hematoxylin and eosin (HE) staining and staining for other markers, including P16 (1:50, ab51243, Abcam, Cambridge, UK), P53 (1:2000, ab32389, Abcam), ER (1:800, 21244-1-AP, Proteintech), PR (1:200,

(12) Tumor senescence leads to poor survival and therapeutic resistance in human breast cancerFrontiers in OncologyMarch 2, 2023Jingtong Zhai, Jiashu Han, Cong Li, Dan Lv, Fei Ma, Binghe XuCD8 (ZA0508, ZSGB-BIO, CHINA), CD68 (ZM0060, ZSGB-BIO,CHINA), PANCK (ZM0069, ZSGB-BIO,CHINA), P16 (ab51243, Abcam, Cambridge, UK), a-SMA (ab7817, Abcam, Cambridge, UK) and CD31 (ab76533, Abcam, Cambridge, UK).

(13) Decreased Enterobacteriaceae translocation due to gut microbiota remodeling mediates the alleviation of premature aging by a high‐fat dietAging CellFebruary 1, 2023Kang Xu, Yannan Guo, Yida Wang, Yu Ren, Vivien Low, Sungyun Cho, Lu Ping, Kezheng Peng, Xue Li, Ying Qiu, et al.Then, it was incubated with primary antibodies against Sirt6 (1:1000, ab62739, Abcam), p16 (1:1000, ab51243, Abcam), p21 (1:1000, ab188224, Abcam), β‐actin (1:1000, 4970S, Cell Signaling Technology), and GAPDH

(14) UCHL1 regulated by Sp1 ameliorates cochlear hair cell senescence and oxidative damageExperimental and Therapeutic MedicineJanuary 9, 2023Lihua Li, Kai Xu, Xue Bai, Zhi Wang, Xiaoyan Tian, Xubo Chen1:2,000; Abcam), anti-Bcl-2 associated X (Bax; cat. no. ab32503; 1:1,000; Abcam), anti-p16 (cat. no. ab51243; 1:1,000; Abcam), anti-p21 (cat. no. ab109199; 1:1,000; Abcam), anti-Sp1 (cat. no. ab227383; 1:1,000;

(15) Retinoblastoma-Binding Protein 5 Regulates H3K4 Methylation Modification to Inhibit the Proliferation of Melanoma Cells by Inactivating the Wnt/β-Catenin and Epithelial-Mesenchymal Transition PathwaysJournal of oncologyJanuary 1, 2023Yang Z, Jia Y, Wang S, Zhang Y, Fan W, Wang X, He L, Shen X, Yang X, Zhang Y, et al.PA5-63522, 1 : 1000; Shanghai, China), H3K4me3 (Abcam, ab8580, 1 : 100; Cambridge, UK), P16 (Abcam, ab51243, 1 : 5000), β-catenin (Abcam, ab32572, 1 : 5000), c-myc (CST, 13987, 1 : 1000; Louisville, KY, USA),

(16) Long noncoding RNA DSCR8 promotes the proliferation of liver cancer cells and inhibits apoptosis via the miR-22-3p/ARPC5 AxisJournal of CancerJanuary 1, 2023Jiu-Ning Huang, Hui-Ming Zhang, Jun-Dong Cai, Wu-Long Wang, Ping Wangsolution. The primary antibodies were monoclonal mouse antibodies against ARPC5 (1:1000, Abcam, Cat#ab51243, Cambridge, UK); β-catenin (1:1000, Abcam, Cat#ab32572, Cambridge, UK); cyclin D1(1:1000, Abcam, Cat#ab16663,

(17) Integrating Network Pharmacology and Experimental Validation to Explore the Pharmacological Mechanism of Astragaloside IV in Treating Bleomycin-Induced Pulmonary FibrosisDrug design, development and therapyJanuary 1, 2023Yuan S, Zuo B, Zhou SC, Wang M, Tan KY, Chen ZW, Cao WF.anti-GAPDH (ab181602), anti-TGF-β1 (ab215715), anti-Vimentin (ab92547), anti-p21 (ab109199), and anti-p16 (ab51243) were obtained from Abcam (Waltham, MA, USA). Collagen I (E8I9Z) was obtained from Cell Signaling Technology

(18) Immunity and reproduction protective effects of Chitosan Oligosaccharides in Cyclophosphamide/Busulfan-induced premature ovarian failure model miceFrontiers in immunologyJanuary 1, 2023Li X, Ye H, Su T, Hu C, Huang Y, Fu X, Zhong Z, Du X, Zheng Y.Abcam), anti-IL-2 (1:200, ab11510, Abcam), anti-IL-4 (1:1000, 66142-1-Ig, Proteintech), anti-p16 (1:2000, ab51243, Abcam), anti-p21(1:1000, 28248-1-AP, Proteintech), and anti-p53 (1:5000, 60283-2-Ig, Proteintech),

(19) D-galactose protects the intestine from ionizing radiation-induced injury by altering the gut microbiomeJournal of radiation researchDecember 6, 2022Zhu T, Wang Z, He J, Zhang X, Zhu C, Zhang S, Li Y, Fan S.After blocking with 5% skim milk, the membranes were probed with an anti-p16 primary antibody (Abcam #ab51243, Cambridge, USA), followed by FluoresceinIsothiocyanate (FITC)-conjugated goat anti-rabbit IgG (H +

(20) miR-146a impedes the anti-aging effect of AMPK via NAMPT suppression and NAD+/SIRT inactivationSignal Transduction and Targeted TherapyDecember 1, 2022Hui Gong et al.from Selleck Chemicals (Houston, TX, USA). Antibodies against NAMPT (ab45890) and CDKN2A/p16INK4a (ab51243) were obtained from Abcam (Cambridge, UK). Antibodies against phosphorylated (p)-AMPKα (Thr172) (40H9),

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4/13/2015Very good p16 antibody for immunoblotting A RWe are evaluating the basal level of DNA damage markers in wild type and clock deficient mutant mice to understand their role in specific pathological processes. We would like to compare stress-... Read Review

Anti-p16 ARC antibody [EP1551Y] from Abcam

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Anti-p16 ARC antibody [EP1551Y] from Abcam

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