IkB-alpha Antibody MAB4299 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemIkB-alpha Antibody
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMAB4299
NCBI Gene AliasesMAD-3, EDAID2, IKBA, NFKBI
ReactivityHuman
Clone417208
HostMouse
Quantity50 ug (also 25 ug)
TargetIkB-alpha
NCBI Full Gene NameNFKB inhibitor alpha
ApplicationsWB, IHC
ClonalityMonoclonal
FormatLyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS
ImmunogenE. coli-derived recombinant human IkB-alpha, Met1-Leu317, Accession # P25963
ConcentrationLYOPH
PurityProtein A or G purified from hybridoma culture supernatant
Brand/TrademarkR&D Systems, a Bio-Techne Brand
ValidationKnockout Validated
Antibody TypePrimary Antibodies
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution
IsotypeIgG1
Conjugate/TagUnconjugated

Specifications/Features

Available conjugates: Unconjugated

Specificity: Detects human IkB-alpha in Western blots

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Interleukin-1α Is a Critical Mediator of the Response of Human Bronchial Fibroblasts to Eosinophilic InflammationCellsMarch 2, 2021Bernau K, Leet JP, Floerke H, Bruhn EM, Noll AL, McDermott IS, Esnault S, Jarjour NN, Sandbo N.(ab76315 Abcam, Cambridge, UK), while mouse monoclonal antibodies were against NFκB inhibitor α (IkBα) (MAB4299, R&D Systems), IkBα (ab12134, Abcam), phospho-IkBα (MA5-15224, Invitrogen, Carlsbad, CA, USA), and β-actin

(2) Manuka Honey Modulates the Inflammatory Behavior of a dHL-60 Neutrophil Model under the Cytotoxic LimitInternational Journal of BiomaterialsFebruary 25, 2019Benjamin A. Minden-Birkenmaier, Kasyap Cherukuri, Richard A. Smith, Marko Z. Radic, Gary L. BowlinScientific) for an hour, and then incubated overnight at 4∘ C in mouse anti-human IKB𝛼 primary antibody (MAB4299, R&D Systems, Minneapolis, MN, USA) at a 0.1 𝜇g/mL concentration and rabbit antihuman phospho-IKB𝛼 (S32/S36)

(3) Targeting Toll-like receptors with soluble Toll-like receptor 2 prevents peritoneal dialysis solution-induced fibrosisKidney internationalAugust 1, 2018Raby AC, González-Mateo GT, Williams A, Topley N, Fraser D, López-Cabrera M, Labéta MO.

(4) Indicaxanthin inhibits NADPH oxidase (NOX)-1 activation and NF-κB-dependent release of inflammatory mediators and prevents the increase of epithelial permeability in IL-1β-exposed Caco-2 cellsBritish Journal of NutritionFebruary 14, 2014L. Tesoriere, A. Attanzio, M. Allegra, C. Gentile, M. A. Livreamilk), followed by incubation with human anti-IkB-a monoclonal antibodies (clone 417208, catalogue no. MAB4299; R&D Systems) or human anti-phospho-IkB-a polyclonal antibodies (S32/S36, catalogue no. AF4809; R&D Systems

(5) Phytochemical indicaxanthin suppresses 7-ketocholesterol-induced THP-1 cell apoptosis by preventing cytosolic Ca²⁺increase and oxidative stressBritish Journal of NutritionJuly 28, 2013Luisa Tesoriere, Alessandro Attanzio, Mario Allegra, Carla Gentile, Maria A. LivreaSanta Cruz Biotechnology), anti-NF-kB with its inhibitor k Ba (Ik-Ba) monoclonal antibody (clone 417208, catalogue no. MAB4299; R&D Systems), anti-phospho-Ik-Ba polyclonal antibody (S32/S36, catalogue no. AF4809; R&D Systems),

(6) ERK5 protein promotes, whereas MEK1 protein differentially regulates, the Toll-like receptor 2 protein-dependent activation of human endothelial cells and monocytesThe Journal of biological chemistryAugust 3, 2012Wilhelmsen K, Mesa KR, Lucero J, Xu F, Hellman J.

Be the First to Write a Review!

IkB-alpha Antibody

IkB-alpha Antibody

IkB-alpha Antibody

IkB-alpha Antibody

IkB-alpha Antibody

IkB-alpha Antibody from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (6)

Reviews

IkB-alpha Antibody from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map