Welcome Guest
Sign In
Register
Products
Popular Categories
Antibody Search
ELISA Kit Search
Biomolecules
Flow Cytometers
Thermal Cyclers
Microscopes
Transfection Reagents
Featured Products
New Products
Articles
Resources
eBooks
Bench Tips
Tech Insights
Editorial Articles
News
Product Reviews
Future Lab
Multimedia
Biocompare Webinars
Immunotherapy
Reproducibility
Transformative Technologies
Podcasts
Tech Talks
Bench Tip Videos
All Videos and Webinars
Life Science Webinars
Write a Review
Antibodies
Kits/Reagents
Equipment
Services
Resources
Promotions
Events
AACR SPOTLIGHT
Register
Sign In
Biocompare
Products
Antibodies
Antibodies
Anti-Notch1 antibody [EP1238Y]
Anti-Notch1 antibody [EP1238Y] from Abcam
(2)
Write a review
Citations:
(166)
Supplier Page
Supplier Page from
Abcam for
Anti-Notch1 antibody [EP1238Y]
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Anti-Notch1 antibody [EP1238Y]
Company
Abcam
Price
Supplier Page
View Company Product Page
Catalog Number
ab52627
Antibody Type
Primary
Isotype
IgG
Clone
EP1238Y
Applications
Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Western blot
Host
Rabbit
Quantity
10 UL, 40 UL, 100 UL
Clonality
Monoclonal
Gene Name
NOTCH1
Validation
KnockOut Validated
Reactivity
Human, Mouse
Target
Notch1
Conjugate/Tag
Unconjugated
Add to Compare List
Abcam
Discovery Drive
Cambridge Biomedical Campus
Cambridge
CB2 0AX
United Kingdom
Phone
: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600
Company Profile
Website:
http://www.abcam.com
Citations (166)
(1)
circAGTPBP1 promotes the progression of papillary thyroid cancer through the notch pathway via the miR-34a-5p/notch1 axis
iScience
September 15, 2023
Dai L, Zhang W, Wang Y, Yu K, Le Q, Wu X.
Proteintech Group, Inc
., Wuhan, China), anti-E-cadherin (cat. #
20874-1-AP
,
Proteintech Group
), anti-NOTCH1 (cat. #
ab52627
,
Abcam
), anti-Hes1 (cat. #
ab71559
,
Abcam
),
anti-Jagged1
(cat. #ab300561, Abcam), and anti-GAPDH (cat.
(2)
PTEN Overexpression Alters Autophagy Levels and Slows Sodium Arsenite-Induced Hepatic Stellate Cell Fibrosis
Toxics
July 3, 2023
Fei Huang, Guanxin Ding, Yanjie Yuan, Lijun Zhao, Wenmeng Ding, Shunhua Wu
ab124964
),
HES1
(
1:1000
) (Abcam Co, UK), PTEN (
1:1000
) (
CST
,
11988S
), NOTCH1 (
1:500
) (
Abcam
Co., UK,
ab52627
), GAPDH (
1:10,000
) (Abcam Co., UK), and β-actin (
1:10,000
) (Abcam Co., UK). The blots were rinsed three
(3)
Effect of the Lipoxin Receptor Agonist BML-111 on Cigarette Smoke Extract-Induced Macrophage Polarization and Inflammation in RAW264.7 Cells
International Journal of Chronic Obstructive Pulmonary Disease
May 19, 2023
En Cao, Jun Xu, Yuanqi Gong, Jingjing Yuan, Anbang Chen, Jiayi Liu, Yunfei Fan, Xiangyang Fan, Xiaodong Kuang
San Francisco, CA, USA), caspase-1 and cleaved caspase-1 (Ab893325, CST, Boston, MA, USA), Notch-1 (
Ab52627
,
Abcam
, San Francisco, CA, USA), activated Notch-1 (
Ab52301
,
Abcam
, San Francisco, CA, USA), and
Hes-1
(4)
Lactobacillus brevis alleviates the progress of hepatocellular carcinoma and type 2 diabetes in mice model via interplay of gut microflora, bile acid and NOTCH 1 signaling
Frontiers in Immunology
May 10, 2023
Shujia Chen, Ping Han, Qian Zhang, Peiyan Liu, Jie Liu, Lili Zhao, Lianyi Guo, Jia Li
4°C with primary antibodies against MMP9 (
1:500
, CatNo:
ab76003
,
Abcam
), NOTCH 1 1 (
1:1000
, CatNo:
ab52627
,
Abcam
),
Hes1
(
1:1500
, CatNo:
ab108937
,
Abcam
),
Math1
(
1:1000
, CatNo,
ab249467
,
Abcam
), and GAPDH (
1:10000
,
(5)
LncRNA H19 mediates BMP9-induced angiogenesis in mesenchymal stem cells by promoting the p53-Notch1 angiogenic signaling axis
Genes & diseases
May 1, 2023
Du C, Cheng Q, Zhao P, Wang C, Zhu Z, Wu X, Gao S, Chen B, Zou J, Huang W,
et al
.
(#
20700-1-AP
,
Proteintech
, China), Collagen Type I (Col1a1, #
14695-1-AP
,
Proteintech
, China), Notch1 (
ab52627
,
Abcam
, USA),
p53
(
ab1101
,
Abcam
, USA), p-p53 (phospho S15) (
ab223868
,
Abcam
, USA) or
GAPDH
(#
10494-1-AP
,
(6)
Notch signaling is activated in knee-innervating dorsal root ganglia in experimental models of osteoarthritis joint pain
Arthritis Research & Therapy
April 15, 2023
Lai Wang, Shingo Ishihara, Jun Li, Rachel E. Miller, Anne-Marie Malfait
sections. Sections were stained overnight at 4 °C with an antibody against active Notch (NICD) (
Abcam
Cat#
ab52627
, RRID:AB_881725;
1:200
), followed by an Alexa Fluor 633-conjugated secondary antibody (Invitrogen,
1:1000
)
(7)
Effect of Hypertrophic Scar Fibroblast-Derived Exosomes on Keratinocytes of Normal Human Skin
International Journal of Molecular Sciences
March 24, 2023
Hui Song Cui, So Young Joo, Seung Yeol Lee, Yoon Soo Cho, Dong Hyun Kim, Cheong Hoon Seo
Cambridge, UK" ASK 1,Rabbit,
1:1000
,"
Abcam
(
ab45178
), Cambridge, UK" Notch 1,Rabbit,
1:1000
,"
Abcam
(
ab52627
), Cambridge, UK" Caspase 14,Rabbit,
1:1000
,"
Abcam
(
ab174847
), Cambridge, UK" Bax,Rabbit,
1:1000
,"
Abcam
(8)
Gut microbe-derived milnacipran enhances tolerance to gut ischemia/reperfusion injury
Cell Reports Medicine
March 21, 2023
Fan Deng, Jing-Juan Hu, Ze-Bin Lin, Qi-Shun Sun, Yue Min, Bing-Cheng Zhao, Zhi-Bin Huang, Wen-Juan Zhang, Wen-Kao Huang, Wei -Feng Liu,
et al.
anti-Cyp1a1 antibody (
ab79819
,
Abcam
), anti-beta catenin antibody (
ab32572
,
Abcam
), anti-Notch1 antibody (
ab52627
,
Abcam
), and anti-Ki67 antibody (
ab16667
,
Abcam
) were used to detect
protein expression
in the intestinal
(9)
TGFBI remodels adipose metabolism by regulating the Notch-1 signaling pathway
Experimental & Molecular Medicine
March 1, 2023
Seul Gi Lee, Jongbeom Chae, Seon Min Woo, Seung Un Seo, Ha-Jeong Kim, Sang-Yeob Kim, David D. Schlaepfer, In-San Kim, Hee-Sae Park, Taeg Kyu Kwon,
et al.
anti-cleaved Notch-1 (Cat. D3B8; Cell Signaling Technology (CST), Danvers, MA, USA), anti-Notch-1 (Cat.
ab52627
;
Abcam
), anti-Hes-1 (Cat. D6P2U; CST), anti-C/EBPα (Cat.
ab15048
;
Abcam
), anti-tubulin (Cat.
2148
;
CST
),
(10)
Frizzled 7 modulates goblet and Paneth cell fate, and maintains homeostasis in mouse intestine
Development
February 15, 2023
Nai-Xin Gu, Yu-Ru Guo, Sey-En Lin, Yen-Hsin Wang, I.-Hsuan Lin, Yi-Fan Chen, Yun Yen
(
1:1000
, Cell Signaling Technology), β-catenin (
1:500
,
BD Biosciences
,
610153
),
Notch1
(
1:100
,
Abcam
,
ab52627
) and
macrophages
(
1:100
,
Abcam
,
ab125148
) detected with Dako REAL EnVision/HRP secondary antibodies
(11)
CDK5RAP2 is a Wnt target gene and promotes stemness and progression of oral squamous cell carcinoma
Cell death & disease
February 11, 2023
Shen Y, Chen Y, Lin Y, Li Y, Liu P, Zhang B, Wang Y, Chan KC, Mak NK, Kahn M,
et al
.
anti-ALDH1 (
1:1000
;
Cell Signaling Technology
, cat. no.
54135
), anti-Notch1 (
1:1000
,
Abcam
, cat. no.
ab52627
), anti-
EZH2
(
1:1000
;
Cell Signaling Technology
, cat. no.
5246
), anti-
CCND1
(
1:1000
,
Cell Signaling Technology
,
(12)
Fetal pulmonary hypertension: dysregulated microRNA-34c-Notch1 axis contributes to impaired angiogenesis in an ovine model
Pediatric Research
February 1, 2023
Devashis Mukherjee, Ujala Rana, Alison J. Kriegel, Pengyuan Liu, Teresa Michalkiewicz, Girija Ganesh Konduri
using ImageJ and normalized to beta-actin. Primary antibodies used were rabbit
Notch1
(
1:1000
,
Abcam
#
ab52627
), rabbit Hey1 (
1:1000
, Abcam catalog # 154077) and rabbit Hes1 (
1:1000
,
Abcam
catalog #
ab71559
).
Angiogenesis assays
(13)
GBP2 promotes M1 macrophage polarization by activating the notch1 signaling pathway in diabetic nephropathy
Frontiers in immunology
January 1, 2023
Li X, Liu J, Zeng M, Yang K, Zhang S, Liu Y, Yin X, Zhao C, Wang W, Xiao L.
1:1000
), anti-NOS (D6B6S, Cell Signaling Technology,
1:1000
), TNF-α (
ab6671
,
Abcam
,
1:1000
), Notch1 (
ab52627
,
Abcam
,
1:1000
), N1ICD (
ab52301
,
Abcam
,
1:1000
), and
GAPDH
(
10494-1-AP
,
Proteintech
,
1:1000
). Horseradish
(14)
Loss of MIR503HG facilitates papillary renal cell carcinoma associated lymphatic metastasis by triggering NOTCH1/VEGFC signaling
International journal of biological sciences
January 1, 2023
Wang Y, Zheng X, Huang W, Lu J, Hou N, Qi J, Ma J, Xue W, Zheng J, Zhai W.
Catalogue Primary antibody:,,
Western blot
:,, anti-β-TUBULIN,
Cell Signaling Technology
,#
2146
anti-NOTCH1,
Abcam
,
ab52627
anti-
VEGFC
,
Cell Signaling Technology
,#
2445
anti-H2A.Z,
Abcam
,
ab150402
anti-YTHDC1
,
Abcam
,ab259990 anti-
HNRNPC
,
Proteintech
,
11760-1-AP
Anti-LAMIN
(15)
Effects of hyperbaric oxygen on Notch signaling pathway after severe carbon monoxide poisoning in mice
Medical Gas Research
January 1, 2023
Hui-Jun Sun, Dan-Feng Fan, Zhou-Heng Fan, Zhou-Heng Sun
incubated overnight at 4°C with primary antibodies for Notch1 (rabbit,
1:1000
, Abcam, Cambridge, UK, Cat#
ab52627
, RRID: AB_881725), Hes5 (rabbit,
1:500
,
Abcam
, Cat#
ab25374
, RRID: AB_448776) and tubulin (
mouse
,
1:10,000
,
(16)
Patchouli alcohol protects against myocardial ischaemia–reperfusion injury by regulating the Notch1/Hes1 pathway
Pharmaceutical Biology
December 31, 2022
Ying Lu, Shou-ye Li, Hui Lou
USA). The antibodies purchased from
Abcam
(UK) used in this study were as follows: anti-Notch1 antibody (
ab52627
), anti-
Hes1
antibody (
ab108937
), anti-
ATF4
antibody (
ab216839
), anti-
PERK
antibody (
ab229912
), anti-phospho-
PERK
(17)
Laminin-integrin a6b4 interaction activates notch signaling to facilitate bladder cancer development
BMC Cancer
December 1, 2022
Nan Hao, Daming Yang, Tianpei Liu, Shucheng Liu, Xinsheng Lu, Libo Chen
Primary antibodies, including anti-integrin α6 (
ab181551
), anti-integrin β4 (
ab133682
), anti-Notch1 (
ab52627
, cleaved intracellular domain of Notch1), anti-JAG1 (
ab109532
), anti-TRB3 (
ab137526
) and anti-β-actin
(18)
Angiopoietin-like 2 is essential to aortic valve development in mice
Communications Biology
November 21, 2022
Pauline Labbé, Victoria Munoz Goyette, Nathalie Thorin-Trescases, Louis Villeneuve, Ines Desanlis, Constance Delwarde, Yan-Fen Shi, Cécile Martel, Carol Yu, Azadeh Alikashani,
et al.
Sigma-Aldrich
);
1:100
diluted rabbit
anti-activated Notch1
(
ab8925
,
Abcam
);
1:100
diluted rabbit anti-Notch1 (
ab52627
,
Abcam
);
1:100
diluted
rat
anti-Integrin α5β1 (
MAB2514
,
Sigma-Aldrich
);
1:100
diluted rabbit anti-PirB
(19)
ED-71 Prevents Glucocorticoid-Induced Osteoporosis by Regulating Osteoblast Differentiation via Notch and Wnt/β-Catenin Pathways
Drug Des Devel Ther
November 15, 2022
Xing Rong, Yuying Kou, Yuan Zhang, Panpan Yang, Rong Tang, Hongrui Liu, Minqi Li
for 1 h and incubated overnight with an anti-β-catenin (
1:200
;
ab32572
,
Abcam
) or anti-Notch1 (
1:200
;
ab52627
,
Abcam
) primary antibody. The next day, cells were incubated for 1 h with a secondary antibody (Alexa
(20)
Lead Exposure Induced Neural Stem Cells Death via Notch Signaling Pathway and Gut-Brain Axis
Oxidative Medicine and Cellular Longevity
October 4, 2022
Lijuan Sun, Yuankang Zou, Peng Su, Chong Xue, Diya Wang, Fang Zhao, Wenjing Luo, Jianbin Zhang
1 : 1000
); LC3 (
Cell Signaling Technology
, #
3868
,
1 : 1000
); Atg 5 (
CST
, #
12994
,
1 : 1000
); Notch1 (
Abcam
,
ab52627
,
1 : 1000
);
RBP-J
(
Abcam
,
ab180588
,
1 : 1000
);
Hes1
(
Abcam
,
ab119776
,
1 : 1000
);
Hes2
(
Abcam
,
ab168071
,
Page
<<
<
1
2
3
4
5
>
>>
Reviews
Write a Review
(1)
2/5/2016
Excellent Anti-Notch1 Antibody from Abcam
Chandan Kumar
Mouse pups were exposed to low oxygen for 5 days, retinal extract were prepared, an equal amount of proteins were resolved in 7.5 % SDS-PAGE, and immunoblotted with anti-Notch1 antibody purchased from...
Read Review
(1)
4/13/2015
Good antibody to detect Notch1
Benjamin Gerovac
Used this antibody to detect Notch1 protein from whole cell lysates. Antibody recognized a single band at the molecular weight shown from the company and had little background signal.
<<
<
>
>>
Anti-Notch1 antibody [EP1238Y] from Abcam
Supplier Page
View Company Product Page
Product Specs
Company Info
Citations
Reviews
Back To Top