Anti-PTP4A3/PRL-R antibody ab50276 from Abcam

Product Specs
ItemAnti-PTP4A3/PRL-R antibody
CompanyAbcam
Price Pricing Info Supplier Page View Company Product Page
Catalog Numberab50276
Antibody TypePrimary
ApplicationsImmunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections), Immunoprecipitation, Western blot
IsotypeIgG
ClonalityPolyclonal
Quantity50 UL
HostRabbit
Conjugate/TagUnconjugated
FormatWhole antiserum is fractionated and then further purified by ion-exchange chromatography to provide the IgG fraction of antiserum that is essentially free of other rabbit serum proteins
Concentration9.4 mg/ml
Gene NamePTP4A3
ReactivityHuman
TargetPTP4A3 / PRL-R

Add to Compare List

Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Phosphatase regenerating liver 3 participates in Integrinβ1/FAK-Src/MAPK signaling pathway and contributes to the regulation of malignant behaviors in hepatocellular carcinoma cellsJournal of Gastrointestinal OncologyApril 29, 2023Guobin Chen, Zhenzhen Zhang, Jinghuan Li, Chao Hu, Dongmei Gao, Jun Chen, Lan Zhang, Xiaoying Xiemethod as detailed previously (21). Briefly, the primary antibody (polyclonal rabbit anti-human PRL-3, ab50276, ABCAM, Cambridge, UK) was diluted 1:400 in phosphate-buffered saline (Hyclone, Logan, Utah, USA) containing

(2) Development and characterization of nanobodies that specifically target the oncogenic Phosphatase of Regenerating Liver-3 (PRL-3) and impact its interaction with a known binding partner, CNNM3PloS oneJanuary 1, 2023Smith CN, Kihn K, Williamson ZA, Chow KM, Hersh LB, Korotkov KV, Deredge D, Blackburn JS.nanobody-beads complex for incubation at 4°C overnight with rocking. For commercial antibodies (Abcam, ab50276; GeneTex, GTX100600; R&D Systems, MAB3219; and Santa Cruz Biotechnology, sc-130355), 3 μg of each antibody

(3) PRL-3 facilitates Hepatocellular Carcinoma progression by co-amplifying with and activating FAKTheranosticsAugust 18, 2020Qiming Zhou et al.points, with other scores defined it low expression. The antibody against PRL-3 was diluted 1:100 (ab50276, Abcam, Cambridge, UK). Other antibodies used for IHC staining included those against the proteins FAK

(4) Up-Regulation of Phosphatase in Regenerating Liver-3 (PRL-3) Contributes to Malignant Progression of Hepatocellular Carcinoma by Activating Phosphatase and Tensin Homolog Deleted on Chromosome Ten (PTEN)/Phosphoinositide 3-Kinase (PI3K)/AKT Signaling PathwayMedical Science MonitorNovember 12, 2018Bing-Hui Li, Yang Wang, Chao-Yang Wang, Ming-Juan Zhao, Tong Deng, Xue-Qun Renmembrane was incubated with the specific primary PRL-3 antibody (anti-PTP4A3, dilution, 1: 500; cat. no. ab50276; Abcam) overnight at 4°C. GAPDH served as an internal control, and the primary GAPDH antibody was bought

(5) PRL-3 promotes gastric cancer peritoneal metastasis via the PI3K/AKT signaling pathway in vitro and in vivoOncology lettersJune 1, 2018Zhang Y, Li Z, Fan X, Xiong J, Zhang G, Luo X, Li K, Jie Z, Cao Y, Huang Z, et al.

(6) PRL-3 promotes breast cancer progression by downregulating p14ARF-mediated p53 expressionOncology LettersDecember 19, 2017Hua Xie, Hao Wangtemperature, the membrane was incubated with primary antibodiesanti-PRL-3 (dilution, 1:500; cat. no. ab50276; Abcam), anti-p53 (dilution, 1:500; cat. no. ab31333; Abcam), anti-p14ARF (dilution, 1:500; cat. no.

(7) PRL‑3 increases the aggressive phenotype of prostate cancer cells inï¿½vitro and its expression correlates with high-grade prostate tumors in patientsInternational Journal of OncologyNovember 20, 2017Donna R. Edwards, Krzysztof Moroz, Haitao Zhang, David Mulholland, Asim B. Abdel-Mageed, Debasis Mondalagainst AR (cat. no. 06680) was from Millipore (Billerica, MA, USA) and antibody against PRL-3 (cat. no. ab50276) was from Abcam (Cambridge, MA, USA). The secondary antibody, TX-Red conjugated goat anti-rabbit IgG

(8) Phosphatase of regenerating liver 3 (PRL-3) is overexpressed in human prostate cancer tissue and promotes growth and migrationJournal of Translational MedicineDecember 1, 2016Esten N. Vandsemb, Helena Bertilsson, Pegah Abdollahi, Øystein Størkersen, Thea Kristin Våtsveen, Morten Beck Rye, Torstein Baade Rø, Magne Børset, Tobias S. SlørdahlDimethyl sulfoxide (DMSO) controls were included since the inhibitor was dissolved in DMSO. The antibodies against PRL-3 (ab50276) and GAPDH were both from Abcam (Cambridge, UK). Gene expression profiling A total of 156 samples were

(9) PRL-3 promotes the peritoneal metastasis of gastric cancer through the PI3K/Akt signaling pathway by regulating PTENOncology reportsOctober 1, 2016Xiong J, Li Z, Zhang Y, Li D, Zhang G, Luo X, Jie Z, Liu Y, Cao Y, Le Z, et al.fluoride (PVDF) membranes were purchased from Millipore (Bedford, MA, USA). PRL-3 antibody [anti-PTP4A3 (ab50276)] was purchased from Abcam (Cambridge, UK) which recognizes human PRL-3 and does not cross-react with

(10) Ubiquitin-Specific Protease 4-Mediated Deubiquitination and Stabilization of PRL-3 Is Required for Potentiating Colorectal OncogenesisCancer researchJanuary 1, 2016Cheng Xing, Xing-Xing Lu, Peng-Da Guo, Tong Shen, Shen Zhang, Xiao-Shun He, Wen-Juan Gan, Xiu-Ming Li, Jing-Ru Wang, Yuan-Yuan Zhao, Hua Wu, Jian-Ming Li

(11) An epigenetic role for PRL-3 as a regulator of H3K9 methylation in colorectal cancerGutApril 1, 2013Yongxia Liu, Ping Zheng, Yuhong Liu, Tianhai Ji, Xunhua Liu, Su Yao, Xing Cheng, Ying Li, Lin Chen, Zhengquan Xiao, Jun Zhou, Jianming Li

(12) Upregulation of Protein Tyrosine Phosphatase Type IVA Member 3 (PTP4A3/PRL-3) is Associated with Tumor Differentiation and a Poor Prognosis in Human Hepatocellular CarcinomaAnnals of Surgical OncologyJanuary 1, 2013Abudureheman Mayinuer, Mahmut Yasen, Kaoru Mogushi, Gulanbar Obulhasim, Maimaiti Xieraili, Arihiro Aihara, Shinji Tanaka, Hiroshi Mizushima, Hiroshi Tanaka, Shigeki Ariiimmunohistochemical studies were performed. The primary antibody used was a polyclonal rabbit anti-human PTP4A3 (ab50276, Abcam, Cambridge, UK), diluted 1:400 in phosphate-buffered saline containing 1 % bovine serum albumin.

(13) Plakophilin3 loss leads to an increase in PRL3 levels promoting K8 dephosphorylation, which is required for transformation and metastasisPloS oneJanuary 1, 2012Khapare N, Kundu ST, Sehgal L, Sawant M, Priya R, Gosavi P, Gupta N, Alam H, Karkhanis M, Naik N, et al.

(14) PRL-3 is essentially overexpressed in primary colorectal tumours and associates with tumour aggressivenessBritish Journal of CancerNovember 18, 2008D G Molleví, A Aytes, L Padullés, M Martínez-Iniesta, N Baixeras, R Salazar, E Ramos, J Figueras, G Capella, A VillanuevaPRL-3 (rabbit anti-PRL-3, Zymed Laboratories, Invitrogen, Carlsbad, MA, USA, and rabbit anti-PRL-3, ab50276 Abcam, Cambridge, UK), diluted 1 : 500 in phosphate-buffered saline (PBS). Reaction was visualised using

Be the First to Write a Review!

Anti-PTP4A3/PRL-R antibody from Abcam

Abcam

Citations (14)

Reviews

Anti-PTP4A3/PRL-R antibody from Abcam

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map