Anti-Caspase-3 antibody ab44976 from Abcam

Product Specs
ItemAnti-Caspase-3 antibody
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab44976
Antibody TypePrimary
HostRabbit
IsotypeIgG
ClonalityPolyclonal
Quantity100 UL
ApplicationsWestern blot
Conjugate/TagUnconjugated
Concentration0.2 mg/ml
Gene NameCASP3
ReactivityHuman
TargetCaspase-3

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Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

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Website: http://www.abcam.com

(1) Taurine alleviates high-fat-high-glucose-induced pancreatic islet β-cell oxidative stress and apoptosis in ratHeliyonDecember 1, 2023Dongdong Zhao, Deqi Yin, Xinxin Wang, Yanxi Li, Miao He, Jianmin Hu, Lin Shumei, Jiancheng YangBioengineering Co. Ltd., Wuhan, China), anti-Caspase-9 (cat. No. Ab25758, Abcam, USA), anti-Caspase-3 (cat. No. Ab44976, Abcam, USA), anti-Cleaved-caspase-3 (cat. No. 9661S, CST, USA), anti-BAX (cat. No. Ab32503, Abcam,

(2) Hexavalent Chromium Inhibited Zebrafish Embryo Development by Altering Apoptosis- and Antioxidant-Related GenesCurr Issues Mol BiolAugust 18, 2023Khoa Dang Dang, Chi Nguyen Quynh Ho, Huy Duc Van, Son Thanh Dinh, Quynh Thi Truc Nguyen, Tram Thi Thuy Nguyen, Xuyen Thi Ngoc Kien, Tuyet Van Dao, Hung Viet Nong, Minh Thai Nguyen, et al.incubated with primary antibodies in a blocking buffer overnight at 4 °C. The anti-caspase 3 antibody (ab44976, Abcam, Cambridge, MA, USA), anti-Bax antibody (ab53154, Abcam, Cambridge, MA, USA), and anti-bcl-2

(3) HDAC I/IIb selective inhibitor Purinostat Mesylate combined with GLS1 inhibition effectively eliminates CML stem cellsBioactive materialsMarch 1, 2023Qiu Q, Yang L, Feng Y, Zhu Z, Li N, Zheng L, Sun Y, Pan C, Qiu H, Cui X, et al.from Cell Signaling Technology, USA. The antibodies against Gls1 (Cat # ab262716), Caspase3 (Cat # ab44976), Bad (Cat # ab32245) and Akt (Cat # ab32038) were purchased from Abcam. The antibodies against Caspase8

(4) LSM12 facilitates the progression of colorectal cancer by activating the WNT/CTNNB1 signaling pathwayOncology ResearchFebruary 9, 2023YAN ZHUANG, CHUNLAN NING, PENGFEI LIU, YANPENG ZHAO, YUE LI, ZHENCHI MA, LULING SHAN, YINGZHE PIAO, PENG ZHAO, XUN JINanti-primary antibodies were as follows: LSM12 (1:1000, ab173292, Abcam, Shanghai, China), caspase-3 (1:1000, ab44976, Abcam, Shanghai, China), Cleaved caspase-3 (1:1000, ab2302, Abcam, Shanghai, China), caspase-9 (1:1000,

(5) Synergistic cardioprotective effects of melatonin and deferoxamine through the improvement of ferritinophagy in doxorubicin-induced acute cardiotoxicityFrontiers in PhysiologyNovember 30, 2022Mira Hanna, Hanan Seddiek, Basma Emad Aboulhoda, George N. B. Morcos, Ahmed M. A. Akabawy, Marawan Abd Elbaset, Abdelsatar Abdelsatar Ibrahim, Mohamed Mansour Khalifa, Ibtesam Mahmoud Khalifah, Mostafa Said Fadel, et al.analysis Immunohistochemical staining with rabbit polyclonal anti-Bax (ab53154), anti-Bcl2 (ab59348), and anti-caspase-3 (ab44976) primary antibodies (IHC-P, at 1:100 dilution, Abcam®, Cambridge, MA, United States) was performed via

(6) Bradykinin postconditioning protects rat hippocampal neurons after restoration of spontaneous circulation following cardiac arrest via activation of the AMPK/mTOR signaling pathwayNeural regeneration researchOctober 1, 2022Lin SR, Lin QM, Lin YJ, Qian X, Wang XP, Gong Z, Chen F, Song B.ab109268, RRID: AB_10888105; Abcam Co.], caspase-3 [an apoptosis-related protein; 1:500; rabbit; Cat# ab44976, RRID: AB_868674; Abcam Co.], and glyceraldehyde 3-phosphate dehydrogenase [1:2000; mouse; Cat# TA-08,

(7) Intravitreal injection of mitochondrial DNA induces cell damage and retinal dysfunction in ratsBiological researchJune 3, 2022Guo Y, Gan D, Hu F, Cheng Y, Yu J, Lei B, Shu Q, Gu R, Xu G.Affinity Biosciences Ltd), rabbit anti-cleaved caspase 9 (AF5240, affbiotech), rabbit anti-caspase 3 (ab44976, Abcam), rabbit anti-cleaved caspase 3 (ab49822, Abcam), anti-β-actin (ab8227, Abcam), anti-cGAS (ab179785,

(8) The 1q21.3 region driver gene EFNA3 promotes disease progression via inhibition of lung adenocarcinoma cell apoptosisTranslational Cancer ResearchMay 1, 2022Chenchen Dong, Peng Li, Yue Wu, Zhong Guo, Rui Hecatalog No. FNab08194), and rabbit anti-human caspase 3 antibody (1:1,000, Abcam, USA, catalog No. ab44976). Statistical analysis Statistical analysis was performed using R 4.0.3 and SPSS 26.0 (https://www.ibm.com/support/pages/downloading-ibm-spss-statistics-26?mhsrc=ibmsearch_a&mhq=SPSS%2026.0%20).

(9) Synergetic protective effect of remote ischemic preconditioning and prolyl 4‑hydroxylase inhibition in ischemic cardiac injuryMolecular Medicine ReportsJanuary 11, 2022Juesheng Yang, Jiajun Xu, Lei Tao, Shiyong Wang, Haiyan Xiang, Yanhua Tangtemperature. The slides were incubated with rabbit anti-caspase-3 primary antibody (1:100; cat. no. ab44976; Abcam) overnight at 4°C, then with Alexa fluor 555-coupled anti-rabbit secondary antibody (4 µg/ml;

(10) Norwogonin attenuates hypoxia-induced oxidative stress and apoptosis in PC12 cellsBMC Complementary Medicine and TherapiesDecember 1, 2021Linlin Jing, Rongmin Gao, Jie Zhang, Dongmei Zhang, Jin Shao, Zhengping Jia, Huiping Maanti-Bcl-2 (1:1000, ab59348, Abcam, UK), anti-Bax (1:500, ab32503, Abcam, UK), anticaspase-3 (1:300, ab44976, Abcam, UK), anticytochrome C (1:1000, ab13575, Abcam, UK) and anti-β-actin (1:2000, ab8227, Abcam,

(11) Tlr2/4 Double Knockout Attenuates the Degeneration of Primary Auditory Neurons: Potential Mechanisms From Transcriptomic PerspectivesFrontiers in Cell and Developmental BiologyOctober 25, 2021Quan Wang et al.for the IHC staining. Primary antibodies against the following antigens were used: Caspase 3 (Abcam, ab44976), p65 (Abcam, ab32536), and p38 (Abcam, ab170099). For immunofluorescence staining, frozen sections

(12) Fecal Microbiota Transplantation Protects the Intestinal Mucosal Barrier by Reconstructing the Gut Microbiota in a Murine Model of SepsisFrontiers in Cellular and Infection MicrobiologySeptember 22, 2021Xiaowei Gai, Huawei Wang, Yaqing Li, Haotian Zhao, Cong He, Zihui Wang, Heling Zhaopolyclonal to MUC2 blocking antibody (MUC2, ab90007, Abcam Ltd.; Occludin, ab168986, Abcam Ltd; caspase 3, ab44976, Abcam Ltd.). The sections were washed with PBS and incubated with a secondary antibody for 30 min,

(13) Macrophages induce the expression of lncRNA ATB via the secretion of TGF‑β to relieve ischemia‑reperfusion injury in cardiomyocytesExperimental and Therapeutic MedicineJune 29, 2021Hong Lin, Wen-Sheng Xu, Xiong-Wei Liu, Zhi Wang, Jiao Yan, Tao ZhangAbcam), Bax (cat. no. ab32503; Abcam), cleaved caspase‑3 (cat. no. ab49822; Abcam), caspase‑3 (cat. no. ab44976; Abcam), IL‑1β (cat. no. ab216995; Abcam), IL‑6 (cat. no. ab6672; Abcam), IL‑10 (cat. no. ab133575;

(14) Naringin attenuates rat myocardial ischemia/reperfusion injury via PI3K/Akt pathway‑mediated inhibition of apoptosis, oxidative stress and autophagyExperimental and Therapeutic MedicineMay 28, 2021Fengwei Li, Zhenjian Zhan, Jin Qian, Chuanbin Cao, Wei Yao, Neng Wangbeclin-1 (1:2,000; cat. no. 3495; Cell Signaling Technology, Inc.) and caspase 3 (1:1,000; cat. no. ab44976, Abcam). Secondary antibody was horseradish peroxidase (HRP) goat anti-Rabbit (1:10,000; cat. no. AS1107;

(15) Controlled decompression alleviates early brain injury in rabbit intracranial hypertension model by regulating apoptosis/necroptosisActa Cirúrgica BrasileiraMay 28, 2021Can Zhang, Yue Wang, Junhui Chen, Shuo Yang, Yuhai WangRabbit antibodies against RIP1 (bs-5805R; Bioss; China), RIP3 (bs-3551R; Bioss; China), caspase-3 (ab44976; Abcam; USA) were probed with the membrane and overnight at 4 °C. HRP-conjugated goat anti-mouse IgG

(16) Costunolide attenuates oxygen‑glucose deprivation/reperfusion‑induced mitochondrial‑mediated apoptosis in PC12 cellsMolecular Medicine ReportsMarch 30, 2021Lanqing Meng, Huixia Ma, Jinni Meng, Tingting Li, Yafei Zhu, Qipeng Zhaoab2013), procaspase-7 (cat. no. ab25900), cleaved-caspase-3 (cat. no. ab32042) and procaspase-3 (cat. no. ab44976) were provided by Abcam. Cleaved-caspase-7 (cat. no. AF4203), cleaved-caspase-9 (cat. no. AF5240) were

(17) Discovery of LAMP-2A as potential biomarkers for glioblastoma development by modulating apoptosis through N-CoR degradationCell communication and signaling : CCSMarch 24, 2021Wang Y, Zhang B, Wang J, Wu H, Xu S, Zhang J, Wang L.ab11419), Bcl-2 (1:300, Santa Cruz,sc-492), Bax (1:300, Santa Cruz, sc-493), Caspase-3(1:500, Abcam, ab44976), Caspase-9 (1:1000, Abcam, ab2013), GAPDH (1:2000, CST, #5174), Hsc70(1:3000, Proteintech, IL, USA,

(18) Glutathione S‑transferase ω 1 promotes the proliferation, migration and invasion, and inhibits the apoptosis of non‑small cell lung cancer cells, via the JAK/STAT3 signaling pathwayMolecular Medicine ReportsNovember 20, 2020Kai Wang, Fu-Lian Zhang, Wei Jia(1:500; cat. no. ab129106; Abcam), anti‑Bax (1:500; cat. no. ab182733; Abcam), anti‑caspase 3 (1:500; cat. no. ab44976; Abcam), anti‑JAK (1:500; cat. no. ab47435; Abcam), anti‑phosphorylated (p)‑JAK (1:500; cat. no. ab138005;

(19) Down-Regulation of Circ_0032833 Sensitizes Colorectal Cancer to 5-Fluorouracil and Oxaliplatin Partly Depending on the Regulation of miR-125-5p and MSI1Cancer Management and ResearchNovember 4, 2020Shouchao Li, Sheng Zheng(anti-MRP-1; ab234098, 1:1000), anti-myeloid cell leukemia-1 (anti-MCL-1; ab32087, 1:1000), anti-caspase-3 (ab44976, 1:1000), anti-N-cadherin (anti-N-cad; ab18203, 1:1000), anti-E-cadherin (anti-E-cad; ab15148, 1:1000),

(20) ISL Induces Apoptosis and Autophagy in Hepatocellular Carcinoma via Downregulation of PI3K/AKT/mTOR Pathway in vivo and in vitroDrug Design, Development and TherapyOctober 20, 2020Lei Song, Yi Luo, Shaoling Li, Ming Hong, Qi Wang, Xiaoling Chi, Cong YangChina). Primary antibodies against Bcl-2 (1:2000, ab182858), Bax (1:5000, ab32503), Caspase-3 (1:500, ab44976), PARP (1:5000, ab32064), p-PI3K (1:1000, ab191606), Akt, P-Akt (Ser473), p-Akt (1:5000, ab81283), and

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Anti-Caspase-3 antibody from Abcam

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Anti-Caspase-3 antibody from Abcam

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